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CSIR - CENTRAL FOOD TECHNOLOGICAL RESEARCH INSTITUTE

COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH

MINISTRY OF SCIENCE & TECHNOLOGY, GOVT. OF INDIA,
MYSURU - 570020

Nanishankar V Harohally

Sr. Scientist

Ph.D in Chemistry from IISc, Postdoctoral Work experience from Univ of Maryland, USA

Email : nani@cftri.res.in

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Expertise

Synthetic Chemistry in particular Organic,Organometallic,Materials,Inorganic.

Spectroscopy in particular NMR, IR and NIR

Important Publications as Corresponding Author

Carbohydrate Chemistry

We are interested in unusual reactions of carbohydrates  relevant to food including Amadori,Heyns and other reactions. Our efforts has lead to following Publications

(1) Debasree .C, Nanishankar V.H. Tet Lett  2018, 59(31), 2983-2988.Revisiting Amadori and Heyns Synthesis: Critical Percentage of Acyclic Form Play the Trick in Addition to Catalyst

https://doi.org/10.1016/j.tetlet.2018.06.050

It is a concept based paper

(2) Nanishankar  et al. J . Agri Food Chem 2017, 65, 8773-78.Antiaflatoxigenic and Antimicrobial Activities of Schiff Bases of 2-Hydroxy-4-methoxybenzaldehyde, Cinnamaldehyde, and Similar Aldehydes

https://doi.org/10.1021/acs.jafc.7b02576

 (3) Nanishankar et al. Food Chem 2014, 158, 340-344(4).ZnCl2-mediated practical protocol for the synthesis of Amadori ketoses

https://doi.org/10.1016/j.foodchem.2014.02.094

(4)  SM Srinivas, Nanishankar VH J . Agri Food Chem 2012, 60 (6), 1522-1527. Improved synthesis of lysine-and arginine-derived Amadori and Heyns products and in vitro measurement of their angiotensin I-converting enzyme inhibitory activity

https://doi.org/10.1021/jf204185y

It is a concept based paper, wherein, one reagent performing two jobs!

Physical Organic Chemistry

We are interested in concept based crystal engineering research and unusual bonds

(1)  A kala, K.Karthik, Nanishankar V.H, NK Lokanath,J of Mol Struct 2020, 1202.127238

Synthesis, characterization and hydrogen bonding attributes of halogen bonded O-hydroxy Schiff bases: Crystal structure, Hirshfeld surface analysis and DFT studies

https://doi.org/10.1016/j.molstruc.2019.127238 

It is a concept based paper.

(2) A kala,  Nanishankar V.H,Naveen, Ramegowda, NK Lokanath Molecular Crystals and Liquid Crystals 2016, 629(1), 146-157

O-hydroxy Schiff bases derived from 2-hydroxy-4-methoxy Benzaldehyde: Synthesis,X-ray studies and hydrogen bonding attributes

https://doi.org/10.1080/15421406.2015.1107814

 


Heterocylic Chemistry

We are interested in Design of heterocylic compounds in view of achieving better antimicrobial compounds.

(1) Bhargava K M, Gururaja R, & Nanishankar V.H, Synth commun 2017, 47 (11), 1065-1070.

Synthesis and antimicrobial activity of Schiff bases derived from 2-chloro quinoline-3-carbaldehyde and its derivatives incorporating 7-methyl-2-propyl-3H-benzoimidazole-5-carboxylic acid hydrazide.

https://doi.org/10.1080/00397911.2017.1309668

 (2) Bhargava K M, Gururaja R, & Nanishankar V.H, Indian Journal  of Heterocyclic Chemistry 2016, 26(1&2) 75-806.

Syntheisis, Characterization and antimicrobial activity Of Schiff bases derived from 2- hydroxyquinoline-3-Carbaldehydes

 

Materials Chemistry

We are interested in Metal-organic framework materials and its application to drug delivery, food bioactive molecule delivery etc

1)Venkataswamy, Gangothri; Meena, Nisha kiran; Naik, Kavya K; Harohally, Nanishankar (2019): Capsaicin Entrapment in Metal-Organic Framework Material Derived from γ-Cyclodextrin. ChemRxiv. Preprint.

https://doi.org/10.26434/chemrxiv.10484192.v1

We found a spicy application for Material reported by Nobel Laurate!

Our group is the first one to publish from CFTRI in a preprint flatform.

Important Publications as Contributing  Author ( Chemistry aspects in particular Structural Elucidation  and others )

1) Desai  NM   Martha ,GS, Nanishankar VH, PS Murthy LWT Food Science and Technolgy  2019. Non-digestible oligosaccharides of green coffee spent and their prebiotic efficiency

https://doi.org/10.1016/j.lwt.2019.108784

2) Mondal S,Pandit  SG, Mohan kumari HP,Nanishankar VH,Mohan A.D Process Biochemistry 2019, 82, 173-178.Structural and functional characterization of new pigment molecule Monashin from Monascus purpureus CFR410-11.

https://doi.org/10.1016/j.procbio.2019.04.004

3) Pandit  SG, Mohan kumari HP,Nanishankar VH,Mohan A.D Food Chem 2018, 255, 89-96.Functional attributes of a new molecule- 2-hydroxymethyl-benzoic acid 2'-hydroxy-tetradecyl ester isolated from Talaromyces purpureogenus CFRM02.

https://doi.org/10.1016/j.foodchem.2018.02.034

4)Siddharth P, Nanishankar VH,RoopavathiC,M.M.Naidu, Scientific Reports 2018, 8(1), 17414.Isolation, identification, structural elucidation and bioactivity of Heneicos-1-ene from Coriandrum sativum L. foliage

https://doi.org/10.1038/s41598-018-35836-z

5)Talawar S,  Nanishankar VH, Chethana R, Sureshkumar G J . Agri Food Chem 2017,65, 9838-9848.Development of Wheat Bran Oil Concentrates Rich in Bioactives with Antioxidant and Hypolipidemic Properties

https://doi.org/10.1021/acs.jafc.7b03440

6)Shobarani P, Nanishankar VH, Halami PM, Sachindra NM Internationl J of Biological Macromolecules 2014, 65, 542-548.Antioxidant and anticoagulant activity of polyphenol and polysaccharides from fermented Sargassum sp.

https://doi.org/10.1016/j.ijbiomac.2014.02.005

Patents:

1. A novel cyclic polyene compound from the leaves of memecyon malabaricum with antiangiogenic, antioxidant and proapoptotic activity

By Dharmappa, Rekha Nangappa Gowda; Krishnamurthy, Jayashree; Aradhya, Somaradhya Mallikarjun; Harohally, Nanishankar Vishwanath

  • From Indian Pat Appl. 
  •  IN 201841022650 A  Publication date(20/12/2019)

Ph.D Publications

(1) Nanishankar et al. Inorg. Chem. 2005, 44, 18, 6203-6210. Dynamics of a cis-Dihydrogen/Hydride Complex of Iridium

https://doi.org/10.1021/ic050266c

(2) Nanishankar et al. Euro J.Inorg.Chem. 2004, 15, 3048-3056.  Synthesis and Characterization of the First Examples of Dicationic Dihydrogen Complexes of Iron and Ruthenium with the PF3 Ligand 

https://doi.org/10.1002/ejic.200400130

(3) Nanishankar et al. Indian Journal of Chemistry 2003

Dicationic dihydrogen complexes of iron with almost no Fe-η2-H2 back-bonding

(4) Majumdar K.K.Nanishankar VH et al Euro J.Inorg.Chem. 2001, 7, 1847-1853. Some new dicationic dihydrogen complexes of ruthenium.

https://doi.org/10.1002/1099-0682(200107)2001:7<1847::AID-EJIC1847>3.0.CO;2-Q

 

 

Area of interest

Carbohydrate chemistry, Metal Organic Frameworks Heterocyclic chemistry, Nano materials, NMR, & NIR methods, Spice bioactive molecules, Application ofNMR and NIR to Interesting food science research problems

Awards and Certificates

Brief Biosketch illumination via Qualification, Awards and Experience

  • MSc in Chemistry from Bangalore University 
  • Qualified IISc entrance exam for Ph.D Program 
  • Qualified CSIR-UGC NET  1999
  • Awarded Ph.D  degree in  2004-2005 from Indian Institute ofScience, Bengaluru
  • Awarded Postdoctoral Fellowship from University of Maryland, USA
  •  Worked for  Multinational Company Cookson Electronics as Research Scientist
  • Scientist since August 2009 at CSIR-CFTRI